Title of article :
Early diagnosis of Wegenerʹs granulomatosis presenting with bilateral facial paralysis and bilateral serous otitis media
Author/Authors :
Emanuele Ferri، نويسنده , , Enrico Armato، نويسنده , , Paolo Capuzzo، نويسنده , , Stefano Cavaleri، نويسنده , , Ferdinando Ianniello، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Wegenerʹs granulomatosis (WG) is a multi-system disease characterized by granuloma formation and widespread necrotizing vasculitis. It classically presents with involvement of the upper and lower respiratory tracts and renal system. Facial nerve palsy and otologic manifestations have been reported during the course of the disease but it is extremely rare as the presenting features. In Literature only one case of bilateral facial palsy as presenting sign of WG is reported. The testing of anticytoplasmic antibodies versus neutrophil polymorphonucleate granules (c-ANCA) are highly specific for the diagnosis of WG, being positive in 97% of the cases. The early diagnosis and the timely medical treatment lead to high rates of remission of an otherwise lethal disease. A case of WG presenting with bilateral facial paralysis and bilateral serous otitis media is reported.
Keywords :
Wegener’s granulomatosis , Bilateral facial paralysis , Serous otitis media , c-ANCA
Journal title :
Auris Nasus Larynx
Journal title :
Auris Nasus Larynx