Title of article :
Degradation of conjugated linoleic acid isomers in the yeast Saccharomyces cerevisiae
Author/Authors :
Aner Gurvitz، نويسنده , , Barbara Hamilton، نويسنده , , Helmut Ruis، نويسنده , , Andreas Hartig، نويسنده , , J. Kalervo Hiltunen and Tuomo Glumoff، نويسنده ,
Abstract :
Propagation of Saccharomyces cerevisiae cells in conjugated linoleic acid (CLA) medium resulted in activation of the transcriptional machinery that responds to fatty acids. Cells utilized efficiently trans-10,cis-12 CLA, but not the corresponding cis-9,trans-11 isomer, probably due to the formation of cis-3,trans-5-dienoyl-CoA intermediates that are recalcitrant to β-oxidation.
Keywords :
Eci1p , Dci1p , Conjugated linoleic acid , Peroxisome , Sps19p , Saccharomyces cerevisiae
Journal title :
Astroparticle Physics
