More controversies about panic disorder: A reply to Klein

In his discussion of McNallyʹs article in Journal of Consulting and Clinical Psychology (64, 88–91, 1996), Klein (1996a, Behaviour, Research and Therapy, 34, 849–853) clarifies and further defends his argument that cognitive-behavior therapy (CBT) researchers must incorporate drug and pill placebo conditions in their trial designs and must demonstrate a significant drug effect before they are entitled to make inferences about CBTʹs antipanic effects. The purpose of this reply is to provide a critique and rebuttal of Kleinʹs arguments.