Author/Authors :
Antonino Cavallari، نويسنده , , Marco Vivarelli، نويسنده , , Antonia DʹErrico، نويسنده , , Roberto Bellusci، نويسنده , , Paolo Scarani، نويسنده , , Emilio DeRaffele، نويسنده , , Bruno Nardo، نويسنده , , Giuseppe Gozzetti، نويسنده ,
Abstract :
A 32-year-old man who had undergone liver transplantation for fulminant hepatitis due to HBV infection developed fatal acute necrotizing pancreatitis on the 60th post-transplant day, while showing signs of intense viral replication. Immunohistochemistry andin situ hybridization of the pancreas following autopsy showed the presence of HBsAg and HBV-DNA in the cytoplasm of acinar cells, together with the picture of necrotizing pancreatitis. Clinical and histological features seems to indicate that pancreatitis was directly caused by HBV infection.