Title of article :
Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial
Author/Authors :
Massimo Filippi، نويسنده , , Marco Rovaris، نويسنده , , Matilde Inglese، نويسنده , , Frederik Barkhof، نويسنده , , Nicola De Stefano، نويسنده , , Steve Smith، نويسنده , , Giancarlo Comi، نويسنده ,
Abstract :
In patients who present with clinically isolated syndromes suggestive of multiple sclerosis, interferon beta-1a is effective in delaying evolution to clinically definite disease and in reducing MRI-measured disease activity. We aimed to assess whether thi