Blockade of HERG channels by HIV protease inhibitors
Author/Authors :
Blake D. Anson، نويسنده , , Joel GR Weaver، نويسنده , , Michael J. Ackerman، نويسنده , , Omobosola Akinsete، نويسنده , , Keith Henry، نويسنده , , Craig T January، نويسنده , , Andrew D Badley، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
5
From page :
682
To page :
686
Abstract :
The HIV protease inhibitor class of antiretroviral drug causes unpredicted adverse effects by changing elements of normal cellular metabolism. A case of QT prolongation in a patient receiving protease inhibitors made us question whether these drugs might