Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern Pages 1175-1181 Rick A Bright, Marie-jo Medina, Xiyan Xu, Gilda Perez-Oronoz, Teresa R Wallis, Xiaohong M Davis, Laura Povinell

Background Adamantanes have been used to treat influenza A virus infections for many years. Studies have shown a low incidence of resistance to these drugs among circulating influenza viruses; however, their use is rising worldwide and drug resistance has