Title of article :
Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial
Author/Authors :
Kristian Reich، نويسنده , , Frank O. Nestle، نويسنده , , Kim Papp، نويسنده , , Jean-Paul Ortonne، نويسنده , , Robert Evans، نويسنده , , Cynthia Guzzo، نويسنده , , Shu Li، نويسنده , , Lisa T Dooley، نويسنده , , Christopher E.M. Griffiths، نويسنده ,
Abstract :
Background
Tumour necrosis factor α (TNFα) is thought to play a part in the pathogenesis of psoriasis. We assessed the efficacy and safety of continuous treatment with infliximab, a monoclonal antibody that binds to and neutralises the activity of TNFα, i