Title of article :
Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial
Author/Authors :
Kim Fox، نويسنده , , Ian Ford، نويسنده , , P Gabriel Steg، نويسنده , , Michal Tendera، نويسنده , , Roberto Ferrari، نويسنده ,
Abstract :
Summary
Background
Ivabradine specifically inhibits the If current in the sinoatrial node to lower heart rate, without affecting other aspects of cardiac function. We aimed to test whether lowering the heart rate with ivabradine reduces cardiovascular dea