Author/Authors :
Toshiaki Ohara، نويسنده , , Takahiro Oto، نويسنده , , Kentaro Miyoshi، نويسنده , , Hiroyuki Tao، نويسنده , , Masaomi Yamane، نويسنده , , Shinichi Toyooka، نويسنده , , Megumi Okazaki، نويسنده , , Hiroshi Date، نويسنده , , Yoshifumi Sano، نويسنده ,
Abstract :
We report a successful case of sirolimus treatment for chylous pleural and peritoneal effusions of lymphangioleiomyomatosis after lung transplantation. A 32-year-old woman underwent living donor lung transplantation. Persistent chylous pleural and peritoneal effusions were seen postoperatively. Pleurodesis by intrathoracic injection of OK-432, minomycin, and somatostatine analog failed to control chylous effusions. However, sirolimus treatment reduced the amount of chylous drainage and improved both chylous pleural and peritoneal effusions.