Title of article :
A comparison of the adverse reactions associated with isosulfan blue versus methylene blue dye in sentinel lymph node biopsy for breast cancer
Author/Authors :
Sarmela Thevarajah، نويسنده , , Tara L. Huston، نويسنده , , Rache M. Simmons، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Background
Sentinel lymph node biopsy (SLNB) is an established means of staging the axilla in patients with breast cancer. Recently, methylene blue dye has been shown to be an efficacious and cost-effective alternative to isosulfan blue. With the increasing popularity of SLNB, the potential complications of isosulfan blue use must be appreciated.
Methods
A literature search for English language articles available on MEDLINE from 1985 to November 2002 using the search terms allergy, allergic reaction, anaphylactic reactions, anaphylaxis, blue dye, breast cancer, isosulfan blue, methylene blue, and sentinel lymph node biopsy identified 24 reports.
Conclusions
The use of isosulfan blue due for SLNB is associated with a significant number of allergic reactions, some of which are life-threatening. Because methylene blue dye has been shown to be equally effective and does not pose a serious risk of serious allergic reactions, it offers an improved technique above isosulfan blue dye for SLNB.
Keywords :
allergic reaction , breast cancer , Methylene blue , Isosulfan blue , Sentinel lymph node biopsy , Anaphylaxis
Journal title :
The American Journal of Surgery
Journal title :
The American Journal of Surgery