Title of article :
Preshunt liver function remains the prominent determinant of survival after portasystemic shunting
Author/Authors :
Sarah M. Cowgill، نويسنده , , Elizabeth Carey، نويسنده , , Desiree Villadolid، نويسنده , , Sam Al-Saadi، نويسنده , , Emmanuel E. Zervos، نويسنده , , Alexander S. Rosemurgy II، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Background
Forty-five years after the development of the Child classification, we sought to determine if hepatic function is still a primary determinant between short-term and long-term survival after portasystemic shunting.
Methods
One hundred forty-six patients underwent small-diameter prosthetic H-graft portacaval shunting (HGPCS). The patients were stratified into 2 groups: those surviving less than 5 years and those surviving more than 5 years. Preoperative data determined Child class and model for end-stage liver disease (MELD) score.
Results
Ninety-four (64%) patients were short-term and 52 (36%) patients were long-term survivors. No significant differences in the cause of cirrhosis, presence of ascites, encephalopathy, or emergency operations were noted between short- and long-term survivors. Preshunt MELD scores were significantly greater with short-term survivors, although actual survival was superior to predicted survival by MELD. Child class was inferior for short-term survivors. Child class and MELD score significantly correlated with survival after portasystemic shunting.
Conclusions
Long-term survival after HGPCS is possible even with severe hepatic dysfunction; however, actual survival is superior to predicted survival. Hepatic dysfunction, as denoted by Child class and MELD, still remains a primary determinant of survival after portasystemic shunting.
Keywords :
Portacaval shunts , portal hypertension , H-graft , Child class , Model for end-stage liver disease score
Journal title :
The American Journal of Surgery
Journal title :
The American Journal of Surgery