Human immunodeficiency viru dieae: Changing pattern of intraocular inflammation Original Reearch Article

Purpoe To evaluate and put into perpective five article in thi iue of the American Journal OF OPHTHALMOLOGY that dicu ocular inflammatory diorder in patient with human immunodeficiency viru (HIV) dieae. Method We drew upon recent obervation concerning the effect of HIV dieae on the immune ytem in an attempt to undertand the current report decribing intraocular inflammation. Reult Intraocular inflammation appear to be dependent on everal factor, including pecific antigenic timuli and the tate of the hot immune ytem. During dynamic change in thee factor, condition may arie that favor inflammatory reaction. Ue of antiretroviral therapie i one mechanim that can effect thee dynamic. Concluion A the immune ytem equilibrate at one extreme or the other (depletion or recontitution), condition favoring inflammation appear to diipate. Retoration of immune function by the ue of combination antiretroviral therapy, including proteae inhibitor, may lead to additional cae of tranient intraocular inflammation in the future.