Tet-retet variability of blue-on-yellow perimetry i greater than white-on-white perimetry in normal ubject Original Reearch Article

Purpoe: To compare long-term fluctuation of blue-on-yellow automated perimetry with white-on-white automated perimetry in normal ubject. Method: White-on-white and blue-on-yellow automated perimetry were performed on a Humphrey Viual Field Analyzer and an Octopu perimeter, both modified for blue-on-yellow perimetry. The tudy ample conited of 31 eye of 31 normal ubject for the Humphrey perimeter and 33 eye of 33 normal ubject for the Octopu perimeter. After one practice eion, each ubject completed four teting eion over a period of 2 to 8 week, each eparated by at leat 1 day. Each teting eion conited of both white-on-white and blue-on-yellow perimetry performed on one eye; the order of the tet wa alternated for ucceive eion. Long-term fluctuation (expreed a tatitical variance) wa calculated for each tet location. Interubject variability (expreed a tatitical variance) acro all ubject wa determined for each tet location. Reult: On the Humphrey perimeter, the long term fluctuation for blue-on-yellow perimetry (4.07 ± 3.07 dB2) wa ignificantly greater than that for white-on-white perimetry (1.97 ± 0.99 dB2; P < .001). Long-term fluctuation increaed a a function of eccentricity for both blue-on-yellow and white-on-white perimetry. hort-term fluctuation wa ignificantly greater for blue-on-yellow (0.46 ± 0.25 dB) than that for white-on-white perimetry (0.29 ± 0.19 dB; P < .02). Finally, the interubject variability wa ignificantly greater in blue-on-yellow (13.2 ± 2.8 dB2) than it wa in white-on-white perimetry (4.25 ± 1.13 dB2; P < .001). imilar reult were found with the Octopu perimeter. Concluion: Long-term fluctuation and hort-term fluctuation of blue-on-yellow perimetry are greater than thoe of white-on-white perimetry in normal ubject. The increaed long-term fluctuation require appropriate tatitical approache when evaluating erial change of blue-on-yellow perimetry.