Infection of the corneal endothelium in herpe implex keratiti

necrotizing tromal keratiti and corneal perforation in the corneal graft. A econd penetrating keratoplaty wa performed. The corneal button wa proceed for hitopathologic, immunohitochemical, and electron microcopic tudie. REULT: Hitopathologically, the corneal endothelium howed viral incluion bodie. Herpe implex viru antigen and viral particle were identified in tromal keratocyte and corneal endothelial cell. CONCLUION: Productive herpe implex viru infection of the corneal endothelial cell may contribute to corneal graft failure in recurrent herpe implex viru infection.