Effect of peribulbar anetheia on ocular blood flow in patient undergoing cataract urgery Original Reearch Article

PURPOE: The effect of extraconal, peribulbar anetheia on ocular blood flow may be caued by concomitant elevation in intraocular preure or direct pharmacologic alteration of vacular tone. We quantified the effect on ocular circulation with a new technique for aement of ocular hemodynamic. METHOD: In a propective tudy, ocular hemodynamic were meaured before and 1 and 5 minute after peribulbar anetheia in 22 eye with age-related cataract. Meaurement included fundu pulation amplitude with a laer interferometric method aeing the pulatile choroidal blood flow and mean blood flow velocity a well a reitive index in the ophthalmic and central retinal artery with Doppler onography. ytemic blood preure and pule were monitored throughout the period of ocular hemodynamic meaurement. REULT: Fundu pulation amplitude decreaed ignificantly after peribulbar anetheia (after 1 minute and 5 minute: −13% and −8%; P< .001). In the central retinal artery, mean blood flow velocity dropped (−15%; P < .001) and reitive index increaed (+3%; P = .02) 1 minute after peribulbar anetheia compared with baeline. There were no change in ophthalmic artery hemodynamic. Intraocular preure wa elevated 1 minute after peribulbar anetheia (+29%; P = .003) but reached baeline value after 5 minute. CONCLUION: Pulatile choroidal blood flow and retinal blood flow velocitie were reduced after peribulbar anetheia. Thee reduction were till preent 5 minute after peribulbar anetheia, when intraocular preure had returned to baeline value. Thi upport the theory of drug-induced vaocontriction after peribulbar anetheia. A lo of viion may be a rik of peribulbar anetheia in patient who have compromied ocular blood flow before urgery.