Idiopathic central retinal vein occluion in a thrombophilic patient with the heterozygou 20210 G/A prothrombin genotype

PURPOE: To report the occurrence of monolateral central retinal vein occluion in a patient with heterozygou 20210 G/A prothrombin genotype, known to be aociated with high thrombophilic rik. METHOD: A monolateral central retinal vein occluion wa diagnoed in a 71-year-old woman, who had uffered from a deep vein thromboi in her left leg at the age of 36 year. Mutation of the gene involved in the coagulation proce were invetigated by DNA polymerae chain reaction. REULT: DNA analyi howed the patient to be heterozygou for the prothrombin 20210 G/A genetic variation. CONCLUION: The 20210 G/A prothrombin gene mutation may be aociated with central retinal vein occluion.