Perifoveal microcirculation before and after vitrectomy for diabetic cytoid macular edema

PURPOE: To quantify the perifoveal microcirculation in diabetic eye before and after ucceful vitreou urgery for cytoid macular edema without poterior vitreou detachment, and to determine whether improvement in perifoveal microcirculation i aociated with improvement in potoperative viual acuity. METHOD: In a propective tudy, vitreou urgery wa performed on 11 eye of nine conecutive diabetic patient with cytoid macular edema, and their mean perifoveal capillary blood flow velocity wa meaured by fluorecein angiography with a canning laer ophthalmocope. Viual acuity wa meaured preoperatively and potoperatively, and the reult were converted to the logarithm of the minimum angle of reolution (logMAR). The correlation between change in logMAR viual acuity and capillary blood flow velocity wa evaluated. REULT: In all nine eye of even patient with ucceful vitreou urgery, the cytoid macular edema reolved within 6 month after urgery, and the mean capillary blood flow velocity wa ignificantly increaed compared with that before urgery (2.19 mm per econd veru 2.68 mm per econd, P = .021); the change in capillary blood flow velocity were ignificantly correlated with the change in the logMAR viual acuity (P = .024). CONCLUION: Vitreou urgery may improve perifoveal microcirculation in the eye of diabetic patient with cytoid macular edema and reolve the macular edema. Improvement of perifoveal microcirculation may be an important factor affecting viual outcome