Randomized clinical trial of cryotherapy veru laer photocoagulation for retinopexy in conventional retinal detachment urgery

PURPOE: To invetigate whether the method of retinopexy influence the viual recovery rate and the breakdown of the blood-ocular barrier after conventional retinal detachment urgery. METHOD: Forty-eight patient (48 eye) with primary rhegmatogenou retinal detachment entered into the tudy. All eye were phakic, had an attached macula, and were cheduled for conventional cleral buckling urgery. Patient were randomly aigned to have either laer or cryotherapy for retinopexy. All viual acuity and flare meaurement were performed by a maked oberver. The interventional procedure wa cryopexy at the time of cleral buckling urgery or potoperative (4 week) laer photocoagulation. Viual acuity teting with ETDR chart and aqueou flare meaurement with laer flare photometry were performed by a maked oberver at tandard interval: preoperatively and 1 day, 7 day, 4 week, and 10 week potoperatively. Analyi of covariance by multiple linear regreion wa ued for tatitical evaluation. REULT: Potoperative flare value from patient receiving cryotherapy were ignificantly higher at each meaurement point in time (P ≤ .001). The viual recovery wa lower in the patient receiving cryotherapy (1 week, P = .003; 4 week, P = .03; 10 week, P = .081). CONCLUION: Laer flare photometry proved ufficiently enitive to quantify an increae in aqueou flare after limited external retinal cryotherapy. Potoperative flare, a a meaure of blood-ocular barrier breakdown, wa ignificantly higher and viual recovery lower in the cryotherapy group. Viual acuity after 10 week wa not ignificantly different between both group.