canning laer polarimetry in a elected group of patient with glaucoma and normal control

PURPOE: To evaluate the ability of canning laer polarimetry to dicriminate between ubject with glaucoma with pecific pattern of viual field defect and normal control. METHOD: Thi cro-ectional, propective tudy in a glaucoma practice, focued on ubject with glaucoma with predefined type of viual field defect, including advanced (group A, N = 14), localized (group L, N = 46), or mixed (diffue and localized) defect (group M, N = 22) and normal control (n = 32). canning laer polarimetry wa performed in one tudy eye per ubject. Two method of analyi were ued: a ubjective analyi, in which examination printout with the image of the optic dik manually blocked were claified by two oberver maked to the diagnoi, and a logitic regreion analyi of the retardation parameter included in the printout. REULT: The oberver correctly identified 97% of the control and 68% of ubject with glaucoma (overall correct claification of 77%), with 93%, 70%, and 47% of patient from group A, L, and M, repectively, being correctly identified. The bet dicrimination obtained with the logitic regreion correctly identified 69% of control and 94% of glaucoma ubject (overall correct claification of 87%). The performance wa only lightly better for cae from group A compared with L and M. CONCLUION: ubjective aement of the canning laer polarimetry tandard printout of ingle eye might not be enitive enough to detect cae of glaucoma with localized or milder mixed type of viual field defect. The dicriminating ability of canning laer polarimetry improve lightly when logitic regreion analyi i employed.