Retinoblatoma in a patient with an X;13 tranlocation and facial abnormalitie conitent with 13q-yndrome

PURPOE: To report a patient with an X;13 tranlocation and facial feature of 13q-yndrome who developed retinoblatoma. DEIGN: Obervational cae report. METHOD: A 9-month-old girl known to have an X;13 chromoomal tranlocation with a break point at 13q12.1 and dymorphic facial feature characteritic of 13q-yndrome preented with leukocoria in her right eye. REULT: By clinical examination, retinoblatoma wa diagnoed in the right eye. CONCLUION: Chromoomal abnormalitie on the long arm of chromoome 13 predipoe to retinoblatoma formation and characteritic facial feature.