Noninfectiou uveiti and pregnancy

Purpoe To report the coure of uveiti dieae activity during pregnancy and the potpartum period in women with noninfectiou uveiti. Deign Obervational cae erie. Method The medical record of women with noninfectiou uveiti and pregnancy during follow-up at a large eye hopital were retropectively reviewed. Patient with pregnancy were included in the tudy if follow-up wa adequate to document the preence or abence of flare-up in uveiti activity during the pregnancy and/or potpartum period. Reult eventy-ix pregnancie among 50 women were included in the tudy. Thirty-three pregnancie were in women with Vogt–Koyanagi–Harada dieae, 19 were in women with Behcet dieae, and 24 were in women with idiopathic uveiti. A flare-up in uveiti activity occurred within the firt 4 month of pregnancy in 49 of 76 cae (64%) and later in pregnancy in 17 cae (22%); no flare-up occurred during pregnancy in 21 cae (28%). An early pregnancy flare-up wa typical of Vogt-Koyanagi-Harada dieae and idiopathic uveiti. A flare-up within 6 month of delivery occurred in 38 of 59 cae (64%) that had adequate examination data available from the potpartum period. The potpartum flare-up wa epecially typical of Behcet dieae. Concluion Many women with noninfectiou uveiti will experience a flare-up in dieae activity within the firt 4 month of pregnancy. Later pregnancy appear to be a time of relative dieae inactivity. Many will experience a rebound in activity within 6 month of delivery.