Frequency and predictor of glaucoma after pediatric cataract urgery

Purpoe To determine the frequency of and identify predictor of chronic glaucoma after pediatric cataract urgery. Deign Interventional cae erie. Method Retropective review at an eye hopital identified 570 eye among 322 patient who underwent limbal-approach urgery without intraocular len implantation at age ≤16 year for cataract unaociated with other ocular anomalie aide from microcornea. Patient had a minimum of 5 yearʹ potoperative follow-up, which included intraocular preure meaurement. The outcome meaure wa the preence or abence of potcataract urgery glaucoma, defined a intraocular preure ≥26 mm Hg, a meaured on at leat two occaion. Reult Mean follow-up wa 9.0 ± 3.1 year (median, 8.1 year; range, 5.0–18.3 year). Glaucoma developed in 118 of 570 patientʹ eye (21%), including 101 of 272 (37%) undergoing urgery at ≤9 month of age and 17 of 298 (6%) undergoing urgery thereafter. Multivariable Cox proportional hazard regreion analyi with adjutment for potential intraubject correlation identified urgery at ≤9 month of age (hazard ratio [HR], 3.8; 95% confidence interval [CI], 1.8–7.7; P < .001), econdary membrane urgery (HR, 2.6; 95% CI, 1.3–5.3; P = .006), microcornea (HR, 1.9; 95% CI, 1.2–3.1; P = .008), and primary poterior capulotomy/anterior vitrectomy (HR, 10.7; 95% CI, 1.4–80.6; P = .02) a predictor of glaucoma. Concluion Chronic glaucoma i common after cataract urgery performed at or before, but not after, a certain age in childhood. The data ugget that thi age threhold i 9 month, but a true threhold occurring at a omewhat later age cannot be fully excluded.