Frequency doubling technology perimetry abnormalitie a predictor of glaucomatou viual field lo

Purpoe To determine whether frequency doubling technology (FDT) perimetry reult predict glaucomatou viual field defect, a aeed by tandard automated perimetry (AP), in a glaucoma upect population. Deign Longitudinal obervational tudy. Method The tudy included 105 eye of 105 glaucoma upect patient, with a mean follow-up time of 41 ± 17 month. Glaucoma upect had either intraocular preure (IOP) higher than or equal to 23 mm Hg or glaucomatou optic neuropathy by tereophotograph aement. All patient had normal AP viual field at baeline. A baeline FDT tet wa performed within 3 month of the normal AP examination. everal baeline FDT parameter and other variable (age, gender, IOP, central corneal thickne, AP viual field indice, and tereophotograph aement) were invetigated by univariate and multivariate Cox proportional hazard model to obtain hazard ratio (HR) and identify factor that predicted which patient had AP glaucomatou viual field lo during follow-up. Reult eventeen patient (16%) developed repeatable AP viual field abnormality during follow-up. An abnormal FDT examination at baeline predicted the development of AP viual field converion in both univariate (HR = 3.17; 95% confidence interval [CI] = 1.22–8.25; P = .018) and multivariate model (Adjuted HR = 3.68; 95% CI = 1.06–12.8; P = .04). The analyi of FDT examination during follow-up revealed that in 59% of converter the FDT abnormalitie preceded AP viual field lo by a much a 4 year. Alo, the initial development of glaucomatou viual field lo a meaured by AP occurred in region that had previouly demontrated abnormalitie on FDT teting. Concluion Functional abnormalitie detected by FDT perimetry were predictive of the future onet and location of AP viual field lo among glaucoma upect patient