Predominant lo of the photopic negative repone in central retinal artery occluion

Purpoe To determine how the photopic negative repone (PhNR) i affected in central retinal artery occluion (CRAO). Deign Obervational cae erie. Method even patient with unilateral CRAO were included. Full-field cotopic and photopic electroretinogram (ERG) including the PhNR were recorded. Each ERG amplitude in the affected eye wa expreed a a percentage of amplitude of the correponding wave in the unaffected eye. Reult Mean of the PhNR amplitude wa reduced to 12.3 ± 11.7% of that of unaffected eye wherea the cone b-wave amplitude wa attenuated to only 73.4 ± 30.4%. Thi reduction of the PhNR amplitude wa more ignificant than that of other wave including the rod b-wave, maximum a-wave and b-wave, cone a-wave and b-wave, and 30 Hz flicker ERG (P< .005). Concluion The PhNR wa everely affected in CRAO depite relative preervation of the cone b-wave, implicating maive lo of ganglion cell and their axon.