Uveiti in Behçet dieae: An analyi of 880 patient

Purpoe We aimed to decribe the demographic and clinical feature, ocular manifetation, complication, viual prognoi, and treatment in a large population of Turkih patient with Behçet uveiti. We alo aimed to compare viual prognoi between male and female ex and between patient who preented before and after 1990. Deign Obervational cae erie. Method A retropective tudy of 880 conecutive patient (1,567 eye) with Behçet uveiti een at the Uveiti ervice, Department of Ophthalmology, Itanbul Faculty of Medicine, Itanbul Univerity, from 1980 to 1998. All patient met the claification criteria of the International tudy Group for Behçetʹ Dieae. Information on the patientʹ ex, age at onet of uveiti, ocular feature, ocular complication, viual acuity, and ytemic treatment wa collected. Reult Five hundred ninety-nine patient (68%) were male and 281 (32%) were female. The mean age at onet of uveiti wa 28.5 year in male and 30 year in female patient. Ocular involvement wa bilateral in 78.1% and unilateral in 21.9% of the patient. Panuveiti wa the mot common form in both exe. Fundu leion a well a ight-threatening complication were more common in male. At the beginning of the follow-up, potential viual acuity wa 0.1 or le in 30.9% of eye in male and 24.2% of eye in female. Kaplan-Meier urvival analyi etimated the rik of loing ueful viion (>0.1) at 5 and 10 year for male and female a 21% v 10% and 30% v 17%, repectively. Male patient who preented in the 1990 had a ignificantly lower rik of loing viion compared with male patient who preented in the 1980. Concluion Behçet uveiti tart frequently around the end of the third decade and ha a male predominance. The dieae i more evere and the rik of loing ueful viion i higher in male than in female. However, thi rik ha been ignificantly reduced in the 1990.