Dry eye in diabetic patient

Purpoe To compare the prevalence of keratoconjunctiviti icca (KC) in a propective cohort of 22,382 diabetic patient with that in the general population. Deign Propective, obervational, cohort tudy. Method etting: A ditrict of Irael’ larget health maintenance organization. tudy population: We followed the electronic medical record of all patient in the ditrict older than 50 year (159,634 patient) between January 1 and December 31, 2003. Of thoe, 22,382 (14.0%) had diabete. obervation procedure: The proportion of ocular lubrication conumer wa compared among diabetic and nondiabetic patient. All HbA1c laboratory tet performed by the diabetic patient were documented (41,910 tet), and glycemic control wa correlated with the conumption of ocular lubrication. main outcome meaure: Ocular lubrication ue by diabetic patient compared with the general population and the relationhip between glycemic control and ocular lubrication ue. Reult After age and gender adjutment, a ignificantly higher percentage of diabetic patient (20.6%) received ocular lubrication, compared with nondiabetic patient (13.8%, P < .001). The difference wa ignificant for all age group and for both exe (P < .001). A imilar ignificant difference wa prominent between diabetic and nondiabetic patient aged 60 to 89 year who were frequent uer of ocular lubrication. Ocular lubrication conumption increaed with poorer glycemic control (mean annual HbA1c level). Multivariate analyi revealed thi effect to be independent of age, ex, place of birth, or place of reidence. Concluion KC i ignificantly more common among diabetic patient. Poor glycemic control correlate with increaed artificial tear ue in diabetic patient.