Relation Between Reduction of Foveal Thickne and Viual Acuity in Diabetic Macular Edema Treated With Intravitreal Triamcinolone

Purpoe To evaluate the correlation between improvement in viual acuity and the reduction of foveal thickne after a ingle intravitreal injection of 4 mg of triamcinolone in diabetic macular edema. Deign Propective, interventional, nonrandomized clinical trial. Method patient In a propective tudy 24 eye with diabetic macular edema were treated with an intravitreal injection of 4 mg of triamcinolone acetonide. main outcome meaure: Bet-corrected logMAR viual acuity and optical coherence tomography were performed at baeline and 3 month after the treatment. Reult At baeline the average foveal thickne wa 462 ± 154 μm (95% confidence interval, 397–527 μm) and at 3 month 257 ±114 μm (95% confidence interval, 209–305 μm) (P< .0001). The bet-corrected logMAR average viual acuity wa 60.5 ± 10.5 (95% confidence interval, 56.0–65.0) ETDR letter at baeline compared with 65.5 ± 11.1 (95% confidence interval, 60.8–70.1) 3 month after the injection (P = .0001). There wa no correlation between the improvement in viual acuity and the reduction of foveal thickne (r = 0.054, P = .8), but there wa a correlation between reduction in foveal thickne and the age of the patient (r = 0.53, P = .008). Concluion A ingle injection of 4 mg of intravitreal triamcinolone acetonide effectively reduce the foveal thickne in diabetic macular edema and improve viual acuity, but there doe not appear to be a trong correlation between the reduction of foveal thickne and the improvement in viual acuity.