Hitologic Correlation of In Vivo Optical Coherence Tomography Image of the Human Retina

Purpoe To correlate in vivo human retina optical coherence tomography (OCT)3 image with hitology. Deign Cae erie. Method Linear OCT3 can through the macula and optic nerve were obtained in three eye of three patient who then underwent exenteration urgery for orbital cancer. OCT3 image were then correlated with hitology. Reult On hitology, two eye were normal, and one eye had dry macular degeneration. The plexiform layer on hitology correlated with the green/yellow area on the OCT3 can, and the nuclear layer correlated with the black area on the OCT3 can. Concluion The author are unaware of previou report correlating hitology to in vivo human retina OCT3 image. Our finding uing human eye are not different from previou animal tudie, in that the plexiform layer are optically highly backcattering and the nuclear layer are not.