Polypoidal Choroidal Vaculopathy in Tilted Dik yndrome and High Myopia With taphyloma

Purpoe To decribe polypoidal choroidal vaculopathy a a complication of tilted dik yndrome and high myopia with taphyloma. Deign Retropective interventional cae erie. Method Thi report wa a multicenter evaluation of ix patient (eight eye) with tilted dik yndrome or high myopia that wa complicated by poterior taphyloma. Complete ophthalmic examination that included fluorecein angiography, optical coherence tomography (OCT), and indocyanine green angiography (ICG-A) wa performed in all patient. Reult All patient had macular abnormalitie and viual lo. Fundu examination and fluorecein angiography howed typical feature of tilted dik yndrome (five patient; ix eye) or high myopia (one patient; two eye) with taphyloma that wa aociated with polypoidal choroidal vaculopathy. OCT and ICG-A confirmed the preence of polypoidal dilation in the choroid. even eye were treated with laer photocoagulation or verteporfin-photodynamic therapy (V-PDT), although one eye did not require treatment. Viual acuity at the final viit had improved in three eye, deteriorated in three eye, and remained unchanged in two eye. Concluion Polypoidal choroidal vaculopathy i a potential caue of viual lo in tilted dik yndrome and high myopia. We potulate that choroidal abnormalitie at the border of taphyloma induce blood-flow diturbance that are imilar to thoe diturbance that are oberved in chronic central erou chorioretinopathy, which i another condition that occaionally i aociated with polypoidal choroidal vaculopathy. The pathogenei remain unclear, and further tudy i required to better undertand the formation of choroidal polypoidal dilation in thee condition.