Diagnotic Ability of the Heidelberg Retina Tomograph 3 for Glaucoma Original Reearch Article

Purpoe To compare the diagnotic ability of the Heidelberg Retina Tomograph 3 (HRT3) and the Heidelberg Retina Tomograph 2 (HRT2) for dicriminating between healthy eye and eye with glaucomatou viual field lo. Deign Retropective cro-ectional tudy. Method Participant were 93 healthy ubject and 90 patient with open-angle glaucoma. All participant underwent imaging of the optic nerve head with the HRT2. Afterward, HRT data alo were analyzed uing verion 3 of the oftware without modifying the optic dik contour line. The receiver operating characteritic (ROC) curve between normal and glaucomatou ubject were plotted for the global tereometric parameter of both oftware verion. Moorfield regreion analyi (MRA) and glaucoma probability core (GP) diagnotic abilitie alo were compared. Reult The parameter with the larget area under the ROC curve were the Frederick . Mikelberg (FM) dicriminant function for the HRT3 (0.948) and the vertical cup-to-dik ratio (0.914) for the HRT2. At a fixed pecificity of 95%, the bet enitivity wa 74.4% for the Reinhard O.W. Burk (RB) dicriminant function of the HRT2 and 83.3% for the FM dicriminant function of the HRT3. The bet enitivity and pecificity pair for the HRT claification were 85.5% and 76.3%, repectively, for overall MRA2, 84.4% and 83.8%, repectively, for overall MRA3, 93.3% and 58.0%, repectively, for the global color-coded GP, and 84.4% and 74.1%, repectively, for the global GP numerical value. Concluion At 95% fixed pecificity, mot HRT3 parameter exhibited at leat the ame enitivity for glaucoma diagnoi a the analogou parameter for the HRT2. The diagnotic ability overall of MRA3 wa imilar to that of the previou verion. GP exhibited higher enitivity and omewhat lower pecificity than the MRA.