Primary Dieae of Corneal Perforation in handong Province, China: A 10-Year Retropective tudy Original Reearch Article

Purpoe To analyze primary dieae of corneal perforation in handong Province, China. Deign Retropective, noncomparative tudy. Method Medical record of 1,056 patient (1,080 eye) with corneal perforation treated from January 1, 1997 through December 31, 2006 at handong Eye Intitute were reviewed retropectively, and primary dieae were evaluated. Reult Corneal perforation mainly were caued by ocular trauma 715 eye (66.8%) and infectiou keratopathy 294 eye (27.5%). In the traumatic eye, corneal penetrating wound accounted for 608 eye (85.0%), followed by exploion injury 42 eye (5.9%), thermal burn 34 eye (4.8%), and chemical injury 29 eye (4.1%). In the infectiou eye, the mot common pathogen were herpe implex viru 124 eye (42.2%), fungu 74 eye (25.2%), and bacterium 20 eye (6.8%). Repeated corneal perforation occurred in nine eye, with primary dieae of herpe implex keratiti (HK; four eye), Mooren ulcer (two eye), necrotizing keratiti and cleratiti (one eye), bacterial keratiti (one eye), and alkali burn (one eye). Corneal graft perforated in 31 eye, reulting from recurrent HK (eight eye), implant autoproteolyi (even eye), bacterial infection (ix eye), recurrent Mooren ulcer (four eye), immunologic rejection (three eye), trauma (two eye), and fungal recurrence (one eye). Concluion Ocular trauma and infectiou keratopathy dominated among the primary dieae of corneal perforation in handong Province, China, during the pat 10 year. HK eem to be the mot common caue of repeated corneal perforation. Recurrent primary dieae and implant autoproteolyi and infection more often reult in graft perforation.