Photodynamic Therapy for Predominantly Hemorrhagic Leion in Neovacular Age-related Macular Degeneration Original Reearch Article

Purpoe To evaluate the repone of eye treated with photodynamic therapy (PDT) for predominantly hemorrhagic leion in neovacular age-related macular degeneration (NVAMD). Deign Conecutive, interventional cae erie. Method A retropective review wa conducted of eye with NVAMD that were treated with PDT for predominantly hemorrhagic ubfoveal leion. Baeline data recorded were patient age, ue of apirin or warfarin, hitory of previou PDT treatment, viual acuity (VA), extent of ubretinal hemorrhage (RH), and central foveal thickne (CFT) and total macular volume (TMV) meaured by optical coherence tomography (OCT). Follow-up VA, RH tatu, and complication were recorded. Reult Twenty-one eye of 21 patient were identified with a mean pottreatment follow-up of 9.4 month. Mean pretreatment VA wa 20/210, and mean RH ize wa 16 dik area. The RH reolved in 18 eye (86%) after a mean of ix month, with a mean VA of 20/210. Mean VA for all eye at mot recent follow-up wa 20/250. Thirteen (62%) of 21 eye exhibited table or improved VA at the mot recent follow-up. VA one year after PDT inverely correlated with patient age (P = .045) and initial RH ize (P = .04) and poitively correlated with pretreatment VA (P = .01). Previou PDT treatment, ue of apirin or warfarin, and OCT data did not ignificantly correlate with VA or RH reolution. Concluion PDT may be an effective treatment for minimizing viual lo in eye with NVAMD and predominantly hemorrhagic leion. Further tudy i warranted to detail the rik-benefit ratio and compare PDT with other treatment modalitie.