Hepatic vascular calcification: An early second trimester sonographic feature of idiopathic infantile arterial calcinosis

Prenatal sonographic diagnosis of idiopathic infantile arterial calcinosis has been limited to the third trimester. We report a monozygotic twin gestation for which an 18-week ultrasound detected the unique finding of hepatic vascular calcification as the earliest feature of the disorder. In contrast to previous reports, second-trimester ultrasound may permit timely diagnosis of idiopathic infantile arterial calcinosis. (Am J Obstet Gynecol 2001;185:1267–8.)