Author/Authors :
Gaetana Palumbo، نويسنده , , Fausto Avanzini، نويسنده , , Claudio Alli، نويسنده , , Maria Carla Roncaglioni ، نويسنده , , Esio Ronchi، نويسنده , , Mario Cristofari، نويسنده , , Alberto Capra، نويسنده , , Susanna Rossi، نويسنده , , Lorenzo Nosotti، نويسنده , , Carlo Costantini، نويسنده , , Cesare Cavalera، نويسنده , , on behalf of the Collaborative Group of the Primary Prevention Projec، نويسنده ,
Abstract :
A randomized controlled open trial studied the effect of vitamin E supplementation (300 mg/day) on clinic and 24-h ambulatory blood pressure (BP) in 142 treated hypertensive patients. After 12 weeks, clinic BP decreased whether or not patients were randomized to vitamin E. Ambulatory BP showed no change in systolic BP and a small decrease in diastolic BP (−1.6 mm Hg, 95% confidence intervals from −2.8 to −0.4 mm Hg), approaching statistical significance in comparison to the control group (P= .06). Vitamin E supplementation thus seems to have no clinically relevant effect on BP in hypertensive patients already under controlled treatment.
Keywords :
hypertension , vitamin E , blood pressurecontrol , ambulatory blood pressure monitoring.
