Author/Authors :
Narsaiah، A. Venkat نويسنده Organic Chemistry Division, Indian Institute of Chemical Technology, Hyderabad, 500007, India. , , Kumar، J. Kranthi نويسنده Organic Chemistry Division, Indian Institute of Chemical Technology, Hyderabad, 500007, India. ,
Abstract :
The T-type calcium channel blocker and anti-ischemic drug, 1-[bis-(4-fluoro phenyl)-methyl]-4-cinnamylpiperazine (1) has been carried out in four steps with an average of 70% yield. This route is very convenient and can be used for large scale preparation of Flunarizine with high yields and at low cost.
