Title of article :
Antidiarrheal Evaluation of Benincasa hispida (Thunb.) Cogn. Fruit Extracts
Author/Authors :
VRUSHABENDRA SWAMY BHYRAPUR MATHAD، نويسنده , , SRIDHAR CHANDANAM، نويسنده , , SREENIVASA RAO THIRUMALA SETTY، نويسنده , , DHANAPAL RAMAIYAN، نويسنده , , BALAMURALIDHAR VEERANNA، نويسنده , , ASHOKA BABU VECHHAM LAKSHMINARAYANASETTRY، نويسنده ,
Issue Information :
فصلنامه با شماره پیاپی سال 2005
Abstract :
The methanolic extract of fruit of Benincasa hispida (BHFE) was evaluated for its antidiarrheal potential against several experimental models of diarrhea in rats. BHFE treated animals showed significant inhibi-tory activity against castor oil induced diarrhea and inhibited PGE2 induced enter pooling in rats. It also showed significant reduction in gastro intestinal motility following charcoal meal in rats. The result ob-tained and establishes the efficacy of BHFE as an antidiarrheal agent.
Keywords :
BHFE , Benicasa hispida , Antidiarrheal , Fruits
Journal title :
Iranian Journal of Pharmacology and Therapeutics
Journal title :
Iranian Journal of Pharmacology and Therapeutics