Author/Authors :
Salehpour، Saghar نويسنده , , Manzor-al-ajdad، Ozra نويسنده Department of Obstetric and Gynecology, Infertility and Reproductive Health Research Center (IRHRC),Shahid Beheshti University (Mc.S), Tehran, Iran , , Neisani Samani، Elham نويسنده , , Abadi، Alireza نويسنده Department of Obstetric and Gynecology, Infertility and Reproductive Health Research Center (IRHRC),Shahid Beheshti University (Mc.S), Tehran, Iran ,
Abstract :
Background: To determine the level of plasma homocysteine in patients with polycystic ovary
syndrome (PCOS) compared with healthy controls.
Materials and Methods: In this prospective case-control study on 85 PCOS women and 83 controls
matched by body mass index (BMI), homocysteine levels were assessed.
Results: The mean level of homocysteine was 16.25 ± 11.94 ?mol/L in patients with PCOS and
11.58 ± 3.82 ?mol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for
hyperhomocysteinemia compared with BMI-matched control women.
Conclusion: These data suggest that homocysteine levels are elevated in the PCOS population.
Further studies are needed to characterize this relationship.
