Dynamics of female sexual hormones in F1 generation female rats (Rattus norvegicus), exposed to potassium dichromate (Cr VI)

The study was carried out on 28 white Wistar adult female rats from F1 generation (derived from females and males exposed for three months before mating to potassium dichromate, 25, 50 and 75 ppm CrVI). F1 generation was exposed in utero and until sexual maturity to the same Cr VI levels. The study pointed out: significant increase of FSH, LH and testosterone seric level, directly correlated to exposure level and significant decrease of estradiol and progesterone seric level, inversely correlated with the exposure level.