Survival Analysis of Colorectal Cancer in Patients Who Underwent Surgical Operation

Colorectal cancer is a common and lethal disease with various distribution of incidence in different parts of the world and it is known as the third most common cause of cancer death in the world. Since several studies in the world represented different survival rates for colorectal cancer, in this study we aimed to determine the survival of a group of Iranian patients and some related factors retrospectively. We studied patients, who were diagnosed pathologically as colorectal cancer, referring to Shariati and Mehr Hospitals in Tehran between 1995 and 2003 for surgical resection of tumor; all of them could be contacted by phone to get further information. Two hundred and thirty-seven patients with colorectal cancer were studied. The male to female ratio was 1.25 and 11.8% of the patients at the time of diagnosis were younger than 40 years. Left colon involvement rather than right colon was three times more common than right colon and nearly half of the patients were diagnosed at the stage the of localized tumor. The overall one and five years survival rates were 80% and 49%, respectively, and had no difference in both sexes (P>0.05). The patients with well-differentiated tumor or with localized tumor had higher survival rate (P<0.05 and P=0.000, respectively). A significant lower five-year survival rate was seen in patients with rectosigmoid involvement. According to our findings, five-year survival rate in these patients was lower than western countries and also we have the higher proportion of young colorectal cancer cases; so we need to plan regular screening program for finding patients and then follow and treat them extensively.