Synthesis a Novel Class of Unsaturated Cyclic Compounds Containing Phosphorus Atom Using Pseudo Four-Component Condensation Reactions

A novel pseudo four-component condensation reaction for the efficient synthesis of 2λ5-[1,2]oxaphosphinin compounds using triphenylphosphine and ethyl bromoacetate in the presence of electron-deficient acetylenic esters without using any catalyst and activation is reported. Fully functionalized 2λ5-[1,2]oxaphosphinin derivatives can be prepared from simple and readily available precursors under neutral conditions