Direct Conversion of Trimethylsilyl and Tetrahydropyranyl Ethers into Their Bromides and Iodides Under Neutral Conditions Using N-Bromo and N-Iodosaccharins in the Presence of Triphenylphosphine

Trimethylsilyl and tetrahydropyranyl ethers were easily converted into their corresponding bromides and iodides with high efficiency and selectivity by N-bromo- and N-iodosaccharins in the presence of triphenylphosphine under neutral conditions. The reaction of trimethyloctyloxysilane as a model compound was studied in different solvents with different ratios of silyl ethers, triphenylphosphine and N-halosaccharin at room temperature, in order to optimize the reaction conditions