An Efficient Catalyst-Free Ring Opening of Epoxides in PEG-300: A Versatile Method for the Synthesis of Vicinal Azidoalcohols

Efficient and regioselective conversion of epoxides to 1,2-azidoalcohols has been carried out by treatment of sodium azide using polyethylene glycol as the reaction medium. The reaction afforded the corresponding products with high regioselectivity under mild reaction conditions