Title of article
EFFECT OF LAMOTRIGINE ON PROPHYLAXIS OF PEDIATRIC CLASSIC MIGRAINE
Author/Authors
Mirzaei، M.G.R. نويسنده Neurologist, Associate Professor Shahrekord University of Medical Sciences , , Azimian، M. نويسنده Neurologist, Associate Professor, University of Welfare & Rehabilitation Sciences , , Moezzi، M. نويسنده Community Medicine Specialist, Associate Professor, Shahrekord University of Medical Sciences , , Vameghi، R. نويسنده Assistant Professor of Pediatrics, Department of Clinical Sciences, Pediatric Neurorehabilitation Research Center, , , RAFIEIAN KOPAEI، M. نويسنده ,
Issue Information
فصلنامه با شماره پیاپی - سال 2009
Pages
4
From page
35
To page
38
Abstract
Objective
This study was conducted to evaluate the preventive effect of lamotringine on migraine aura and migraine attacks in children, afflicted with classic migraine.
Material & Methods
Conducted between October 2005 and April 2008 in the neurology clinic of Kashani hospital, Shahrekord, this study was a clinical trial, aimed at evaluating the prophylactic effects of Lamotringine administered to 21 children suffering from migraine with aura.
Results
Of the subjects, 52.4% of patients were female. The most common type of aura was visual (42.9%). Following use of Lamotrigine, significant reductions were seen in the frequency (from 5 ± 0.83 to 3.04 ± 1.65) and in intensity (from 6. 33 ± 1.08 to 3.66 ± 1.1) of migraine aura (P= 0.002). After 6 months of drug usage 66.6% of patients were improved.
Conclusion
Lamotringine is effective in reducing the migraine aura and intensity of attacks in patients suffering from migraine with aura, and is hence beneficial for prophylactic therapy in children with classic migraine.
Journal title
Iranian Journal of Child Neurology (IJCN)
Serial Year
2009
Journal title
Iranian Journal of Child Neurology (IJCN)
Record number
669052
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