Effect of Zinc Oxide Supplementation on Some Serum Biochemical Values in Male Broilers

One hundred eight (Ross-308) strain chicks, were randomly divided into 3 treatments (A: basal diet, B: basal diet + 50 ZnO ppm and C: basal diet +100 ZnO ppm) with 3 replicates of 12 birds per treatment, to investigate the effect of Zinc oxide (ZnO) supplement on serum lipoproteins, lipid peroxidation and some enzymes activities in male broilers from 21 to 42 days. At the end of this period, the chicks were fasted for 6 hours and then 2 birds were randomly chosen from each pen for analysis of some serum parameters. Results revealed that in group C (which fed on 100 ppm ZnO) malondialdehyede (MD A) values were lower and total antioxidant status (TAS) and high density lipoprotein cholesterol (HDL-C) values were higher than those of other groups (P<0.05).Also, the levels of ZnO supplement had no significant effect on serum cholesterol (CHOL), low density lipoprotein cholesterol (LDL-C), triglyceride (TRG), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) activity. In conclusion, ZnO supplement (100 ppm), improved the antioxidant defense mechanisms, HDL-C and reduced MDA levels as an index of lipid peroxidation in serum.