The Impact of Silver Nano Particles on Growth Performance, Lymphoid Organs and Oxidative Stress Indicators in Broiler Chicks

This research was carried out to evaluate effects of different levels of nanosilver (Ag-NPs) on growth performance, lymphoid organs and oxidative stress indicators in broiler chicks. A total of 240, one-day-old male broiler chick (Ross 308) was allocated in a completely randomized design (CRD) with four groups and 15 birds in each experimental pen. Birds of Water intake were supplemented with 0 (Control) or 5, 15 and 25 ppm Ag-NPs (Diameter 14±9.8 nm) throughout this research (42 days). Body weight, Feed intake recorded as weekly recorded during research and calculated overall growth performance at the final of study. At the end of the research, one bird with closest weight to any of treatment weight selected. Take of blood samples from birds and removed serum by centrifuge. Serum stored at-20°C until analysis. Immediately after slaughtered of birds, lymphoid organs such as spleen, thymus and bursa of Fabricus removed and relative weights was expressed as percentage of live body weight. Results showed that, nano-silver had no effect on performance. Weight of bursa had significantly decreased in comparison with control treatment (p<0.05) and, lowest weight among treatments observed in treatment that supplemented with 25 ppm nanosilver. Ag-NPs, had significant affect on concentration oxidative stress indicators activity among treatment in comparison to control group (p<0.05). It was concluded that Ag-NPs: 1) No positive effect on performance of broilers, 2) As one of the factors induced oxidative stress and, 3) It is may be decreased immune system. In addition, investigation of these effects need to further research.