Title of article :
Preferential Solvation of Ibuprofen and Naproxen in Aqueous 1,2-Propanediol
Author/Authors :
Yizhak Marcus، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
Abstract :
The recently published study of the solubility of ibuprofen (IBP) and naproxen (NAP) in aqueous 1,2-propanediol (PG) at several temperatures had as its purpose the modeling of the solubilities in terms of the solvent composition. It did not show how these drugs are preferentially solvated by water and by PG. The inverse Kirkwood-Buff integral (IKBI) and the quasi-lattice quasi-chemical (QLQC) approaches are here applied to this problem of the preferential solvation. The interactions involved are deduced from the results.
Keywords :
2-Propanediol , inverse Kirkwood Buff integrals , 1 , naproxen , IBUPROFEN , Preferential solvation , quasi-lattice quasi chemical method
Journal title :
Acta Chimica Slovenica
Journal title :
Acta Chimica Slovenica