Title of article
Synthesis and Biological Evaluation of Novel Chalcone-Porphyrin Conjugates
Author/Authors
Vanda Vaz Serra، نويسنده , , Fatima Camoes، نويسنده , , Sandra I. Vieira، نويسنده , , Maria A. F. Faustino، نويسنده , , Joao P. C. Tome، نويسنده , , Diana C. G. A. Pinto، نويسنده , , Maria G. P. M. S. Neves، نويسنده , , Augusto C. Tome، نويسنده , , Artur M. S. Silva، نويسنده , , Edgar F. da Cruz e Silva، نويسنده , , Jose A. S. Cavaleiro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
9
From page
603
To page
611
Abstract
Studies on the synthesis, structural characterization and biological evaluation of novel chalcone-porphyrin derivatives are described. The photodynamic effect, intracellular localization and cellular uptake of the new conjugates were evaluated in vitro in COS-7 cells. All derivatives exhibited high stability and yielded good fluorescence under light irradiation. None of the chalcone-porphyrins proved to be cytotoxic and/or phototoxic for COS-7 cells.
Keywords
Fluorine , medicinal applications , chalcones , Porphyrins , Fluorophores
Journal title
Acta Chimica Slovenica
Serial Year
2009
Journal title
Acta Chimica Slovenica
Record number
672139
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