Synthesis, Spectroscopic Characterization and Antibacterial Activity of some Chloro Dimethylsulphoxide/ Tetramethylenesulphoxide Ruthenium (II)/(III) Complexes with 1, 2, 3-Benzotriazole

Synthesis and characterization of seven ruthenium (II) and ruthenium (III) chloro sulphoxide complexes with 1, 2, 3- benzotriazole are reported. Three different formulations exist: [cis,fac–RuCl2(so)3(btz)]; [trans–RuCl2(so)3(btz)] and [trans–RuCl4(so)(btz)]–[X]+; where so=dimethylsulphoxide/ tetramethylenesulphoxide; btz = 1, 2, 3-benzotriazole and [X]+ = [(btz)H]+ or Na+. These complexes were characterized by elemental analysis, conductivity measurements, magnetic susceptibility, FT-IR, 1H-NMR, 13C{1H}-NMR and electronic spectroscopy. Complexes were screened for their antibacterial activity and found more potent than 1, 2, 3-benzotriazole ligand and precursor ruthenium compounds against gram-negative bacteria Escherichia coli. All the samples were compared with antibiotic Chloramphenicol for reference.