Fuzzy Logic controller for Hemodialysis Machine Based on Human Body Model

Fuzzy controllers are being used in various control schemes. The aim of this study is to adjust the hemodialysis machine parameters by utilizing a fuzzy logic controller (FLC) so that patient’s hemodynamic condition remains stable during hemodialysis treatment. For this purpose, a comprehensive mathematical model of the arterial pressure response during hemodialysis, including hemodynamic, osmotic, and regulatory phenomena has been used. The multi-input multi-output (MIMO) fuzzy logic controller receives three parameters from the model (heart rate, arterial blood pressure, and relative blood volume) as input. According to the changes in the controller input values and its rule base, the outputs change so that the patient’s hemodynamic condition remains stable. The results of the simulations illustrate that applying the controller can improve the stability of a patient’s hemodynamic condition during hemodialysis treatment and it also decreases the treatment time. Furthermore, by using fuzzy logic, there is no need to have prior knowledge about the system under control and the FLC is compatible with different patients.